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Primed CRISPR-Cas Adaptation and Impaired Phage Adsorption in Streptococcus mutans

Streptococcus mutans strain P42S possesses a type II-A CRISPR-Cas system that protects against phage infection and plasmid transformation. The analysis of 293 bacteriophage-insensitive mutants (BIMs) obtained upon exposure to the virulent phage M102AD revealed the acquisition of 399 unique spacers,...

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Detalles Bibliográficos
Autores principales: Mosterd, Cas, Moineau, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265633/
https://www.ncbi.nlm.nih.gov/pubmed/34011685
http://dx.doi.org/10.1128/mSphere.00185-21