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Primed CRISPR-Cas Adaptation and Impaired Phage Adsorption in Streptococcus mutans
Streptococcus mutans strain P42S possesses a type II-A CRISPR-Cas system that protects against phage infection and plasmid transformation. The analysis of 293 bacteriophage-insensitive mutants (BIMs) obtained upon exposure to the virulent phage M102AD revealed the acquisition of 399 unique spacers,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265633/ https://www.ncbi.nlm.nih.gov/pubmed/34011685 http://dx.doi.org/10.1128/mSphere.00185-21 |