Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response

To study how the Zika virus (ZIKV) interacts with the host unfolded protein response (UPR), we undertook a kinetics study. We show that ZIKV infection triggers an atypical tripartite UPR in A549 cells involving transient activation of the effectors X-box-binding protein 1, activating transcription f...

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Detalles Bibliográficos
Autores principales: Mufrrih, Mohammed, Chen, Biyao, Chan, Shiu-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265652/
https://www.ncbi.nlm.nih.gov/pubmed/34106769
http://dx.doi.org/10.1128/mSphere.00361-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265652/
https://www.ncbi.nlm.nih.gov/pubmed/34106769
http://dx.doi.org/10.1128/mSphere.00361-21

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