SGLT1 Knockdown Attenuates Cardiac Fibroblast Activation in Diabetic Cardiac Fibrosis

Background: Cardiac fibroblast (CF) activation is a hallmark feature of cardiac fibrosis in diabetic cardiomyopathy (DCM). Inhibition of the sodium-dependent glucose transporter 1 (SGLT1) attenuates cardiomyocyte apoptosis and delays the development of DCM. However, the role of SGLT1 in CF activatio...

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Detalles Bibliográficos
Autores principales: Lin, Hui, Guan, Le, Meng, Liping, Uzui, Hiroyasu, Guo, Hangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265780/
https://www.ncbi.nlm.nih.gov/pubmed/34248645
http://dx.doi.org/10.3389/fphar.2021.700366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265780/
https://www.ncbi.nlm.nih.gov/pubmed/34248645
http://dx.doi.org/10.3389/fphar.2021.700366

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