Growth Hormone Receptor Gene Disruption in Mature-Adult Mice Improves Glucose Metabolism and Lifespan in Females

Growth hormone (GH) serves an important role in early and adult life. Reduction of GH action has been shown to increase life span in many species of animals. In fact, mice bearing a congenital disruption of GH receptor (GHR) gene (GHRKO) hold the record for the longest-lived laboratory mice. In addi...

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Detalles Bibliográficos
Autores principales: Duran-Ortiz, Silvana, List, Edward O, Bell, Stephen, Basu, Reetobrata, Young, Jonathan, McHugh, Todd, Mathes, Samuel Casey, Funk, Kevin Ray, Qian, Yanrong, Berryman, Darlene E, Kopchick, John Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265872/
http://dx.doi.org/10.1210/jendso/bvab048.910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265872/
http://dx.doi.org/10.1210/jendso/bvab048.910

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