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The role of NOTCH3 variants in Alzheimer's disease and subcortical vascular dementia in the Chinese population

AIMS: NOTCH3 gene mutations predominantly cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, a common etiology of subcortical vascular dementia (SVaD). Besides, there may be a pathogenic link between NOTCH3 variants and Alzheimer's disease (AD). We...

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Detalles Bibliográficos
Autores principales: Guo, Lina, Jiao, Bin, Liao, Xinxin, Xiao, Xuewen, Zhang, Weiwei, Yuan, Zhenhua, Liu, Xixi, Zhou, Lu, Wang, Xin, Zhu, Yuan, Yang, Qijie, Wang, Junling, Tang, Beisha, Shen, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265940/
https://www.ncbi.nlm.nih.gov/pubmed/33942994
http://dx.doi.org/10.1111/cns.13647