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BAPTA, a calcium chelator, neuroprotects injured neurons in vitro and promotes motor recovery after spinal cord transection in vivo

AIM: Despite animal evidence of a role of calcium in the pathogenesis of spinal cord injury, several studies conducted in the past found calcium blockade ineffective. However, those studies involved oral or parenteral administration of Ca++ antagonists. We hypothesized that Ca++ blockade might be ef...

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Detalles Bibliográficos
Autores principales: Kang, Kyu‐ree, Kim, Jin, Ryu, Bokyeong, Lee, Seul‐Gi, Oh, Min‐Seok, Baek, Jieun, Ren, Xiaoping, Canavero, Sergio, Kim, C‐Yoon, Chung, Hyung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265943/
https://www.ncbi.nlm.nih.gov/pubmed/33942993
http://dx.doi.org/10.1111/cns.13651