Inhibition of hyperactivity of the dorsal raphe 5‐HTergic neurons ameliorates hippocampal seizure

AIMS: Epilepsy, frequently comorbid with depression, easily develops drug resistance. Here, we investigated how dorsal raphe (DR) and its 5‐HTergic neurons are implicated in epilepsy. METHODS: In mouse hippocampal kindling model, using immunochemistry, calcium fiber photometry, and optogenetics, we...

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Detalles Bibliográficos
Autores principales: Cheng, Heming, Qi, Yingbei, Lai, Nanxi, Yang, Lin, Xu, Cenglin, Wang, Shuang, Guo, Yi, Chen, Zhong, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265946/
https://www.ncbi.nlm.nih.gov/pubmed/33955651
http://dx.doi.org/10.1111/cns.13648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265946/
https://www.ncbi.nlm.nih.gov/pubmed/33955651
http://dx.doi.org/10.1111/cns.13648

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