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Inhibition of hyperactivity of the dorsal raphe 5‐HTergic neurons ameliorates hippocampal seizure
AIMS: Epilepsy, frequently comorbid with depression, easily develops drug resistance. Here, we investigated how dorsal raphe (DR) and its 5‐HTergic neurons are implicated in epilepsy. METHODS: In mouse hippocampal kindling model, using immunochemistry, calcium fiber photometry, and optogenetics, we...
Autores principales: | Cheng, Heming, Qi, Yingbei, Lai, Nanxi, Yang, Lin, Xu, Cenglin, Wang, Shuang, Guo, Yi, Chen, Zhong, Wang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265946/ https://www.ncbi.nlm.nih.gov/pubmed/33955651 http://dx.doi.org/10.1111/cns.13648 |
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