NNC 26-9100 increases Aβ1-42 phagocytosis, inhibits nitric oxide production and decreases calcium in BV2 microglia cells

Microglia are the resident immune cell of the brain involved in the development and progression of Alzheimer’s disease (AD). Modulation of microglia activity represents a potential mechanism for treating AD. Herein, the compound NNC 26–9100 (NNC) was evaluated in toxicity, nitric oxide release, Aβ(1...

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Detalles Bibliográficos
Autores principales: Schober, Joseph, Polina, Jahnavi, Walters, Field, Scott, Nathan, Lodholz, Eric, Crider, Albert, Sandoval, Karin, Witt, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266108/
https://www.ncbi.nlm.nih.gov/pubmed/34237100
http://dx.doi.org/10.1371/journal.pone.0254242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266108/
https://www.ncbi.nlm.nih.gov/pubmed/34237100
http://dx.doi.org/10.1371/journal.pone.0254242

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