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Impact of prior Dengue immunity on Zika vaccine protection in rhesus macaques and mice

Pre-existing immunity to flaviviruses can influence the outcome of subsequent flavivirus infections. Therefore, it is critical to determine whether baseline DENV immunity may influence subsequent ZIKV infection and the protective efficacy of ZIKV vaccines. In this study, we investigated the impact o...

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Detalles Bibliográficos
Autores principales: Larocca, Rafael A., Abbink, Peter, Ventura, John D., Chandrashekar, Abishek, Mercado, Noe, Li, Zhenfeng, Borducchi, Erica, De La Barrera, Rafael A., Eckels, Kenneth H., Modjarrad, Kayvon, Busch, Michael P., Michael, Nelson L., Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266125/
https://www.ncbi.nlm.nih.gov/pubmed/34170962
http://dx.doi.org/10.1371/journal.ppat.1009673