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Germline and Somatic mutations in postmenopausal breast cancer patients

OBJECTIVES: In breast cancer (BC) patients, the frequency of germline BRCA mutations (gBRCA) may vary according to the ethnic background, age, and family history of cancer. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) is the second most common somatic mutated gene...

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Detalles Bibliográficos
Autores principales: Nagy, Tauana Rodrigues, Maistro, Simone, Encinas, Giselly, Katayama, Maria Lucia Hirata, Pereira, Glaucia Fernanda de Lima, Gaburo-Júnior, Nelson, Franco, Lucas Augusto Moyses, de Gouvêa, Ana Carolina Ribeiro Chaves, Diz, Maria del Pilar Estevez, Leite, Luiz Antonio Senna, Folgueira, Maria Aparecida Azevedo Koike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266163/
https://www.ncbi.nlm.nih.gov/pubmed/34287479
http://dx.doi.org/10.6061/clinics/2021/e2837