Cargando…

ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) is currently the leading cause of end-stage renal disease globally. The endothelial-to-mesenchymal transition (EndMT) of glomerular endothelial cells has been reported to play a crucial role in DN. As a specific form of epithelial-to-mesenchymal transition, EndM...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Lihong, Zhong, Ziwen, Gu, Jiahui, Nan, Ke, Zhu, Minmin, Miao, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266168/
https://www.ncbi.nlm.nih.gov/pubmed/34238215
http://dx.doi.org/10.1186/s10020-021-00339-7