Generation of Affinity Purified Antibody Reagents for Specific Determination of Efruxifermin in Biological Matrices

Efruxifermin (EFX) is a novel Fc-fusion analog of human fibroblast growth factor 21 (FGF21), currently in clinical development as a potential treatment for non-alcoholic steatohepatitis (NASH). Each molecule of EFX consists of two modified FGF21 molecules, each attached at their N-termini to a human...

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Detalles Bibliográficos
Autores principales: Kinne, Adam S, Abdeen, Sanofar J, Parmer, Elijah S, Thystrup, Jennifer A, Tillman, Erik J, Rolph, Timothy P, Bowsher, Ronald R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Cardiovascular Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266200/
http://dx.doi.org/10.1210/jendso/bvab048.585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266200/
http://dx.doi.org/10.1210/jendso/bvab048.585

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