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Effects of Withdrawal from Cocaine Self-Administration on Rat Orbitofrontal Cortex Parvalbumin Neurons Expressing Cre recombinase: Sex-Dependent Changes in Neuronal Function and Unaltered Serotonin Signaling

The orbitofrontal cortex (OFC) is a brain region involved in higher-order decision-making. Rodent studies show that cocaine self-administration (CSA) reduces OFC contribution to goal-directed behavior and behavioral strategies to avoid drug intake. This change in OFC function persists for many weeks...

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Detalles Bibliográficos
Autores principales: Wright, Andrew M., Zapata, Agustin, Hoffman, Alexander F., Necarsulmer, Julie C., Coke, Lamarque M., Svarcbahs, Reinis, Richie, Christopher T., Pickel, James, Hope, Bruce T., Harvey, Brandon K., Lupica, Carl R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266218/
https://www.ncbi.nlm.nih.gov/pubmed/34083381
http://dx.doi.org/10.1523/ENEURO.0017-21.2021