Tetralone derivatives are MIF tautomerase inhibitors and attenuate macrophage activation and amplify the hypothermic response in endotoxemic mice

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine playing crucial role in immunity. MIF exerts a unique tautomerase enzymatic activity that has relevance concerning its multiple functions and its small molecule inhibitors have been proven to block its pro-inflammatory effec...

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Detalles Bibliográficos
Autores principales: Garai, János, Krekó, Marcell, Őrfi, László, Jakus, Péter Balázs, Rumbus, Zoltán, Kéringer, Patrik, Garami, András, Vámos, Eszter, Kovács, Dominika, Bagóné Vántus, Viola, Radnai, Balázs, Lóránd, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266241/
https://www.ncbi.nlm.nih.gov/pubmed/34225560
http://dx.doi.org/10.1080/14756366.2021.1916010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266241/
https://www.ncbi.nlm.nih.gov/pubmed/34225560
http://dx.doi.org/10.1080/14756366.2021.1916010

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