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Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis

Background: Subarachnoid hemorrhage (SAH) is a life-threatening disease worldwide, and effective pharmaceutical treatment is still lacking. Celastrol is a plant-derived triterpene which showed neuroprotective potential in several types of brain insults. This study aimed to investigate the effects of...

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Detalles Bibliográficos
Autores principales: Xu, Hangzhe, Cai, Yong, Yu, Mengyan, Sun, Jing, Cai, Jing, Li, Jingbo, Qin, Bing, Ying, Guangyu, Chen, Ting, Shen, Yongfeng, Jie, Liyong, Xu, Demin, Gu, Chi, Wang, Chun, Hu, XiaoYi, Chen, Jingsen, Wang, Lin, Chen, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266331/
https://www.ncbi.nlm.nih.gov/pubmed/34182541
http://dx.doi.org/10.18632/aging.203221