GPR30-mediated HMGB1 upregulation in CAFs induces autophagy and tamoxifen resistance in ERα-positive breast cancer cells

Tamoxifen (TAM) resistance constitutes a challenge in managing estrogen receptor (ER)α+ breast cancer patients. G-protein-coupled estrogen receptor (GPR30/GPER), which reportedly initiates TAM resistance in ERα+/ GPR30+ breast cancers, is detected in the breast cancer microenvironment, especially ca...

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Detalles Bibliográficos
Autores principales: Liu, Li, Liu, Shengchun, Luo, Haojun, Chen, Chenxi, Zhang, Xiaoling, He, Lin, Tu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266353/
https://www.ncbi.nlm.nih.gov/pubmed/34182538
http://dx.doi.org/10.18632/aging.203145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266353/
https://www.ncbi.nlm.nih.gov/pubmed/34182538
http://dx.doi.org/10.18632/aging.203145

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