The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence

Cellular senescence may be a side effect of chemotherapy and other anti-cancer treatments that may promote inflammation and paracrine secondary senescence in healthy tissues. DNMT2/TRDMT1 methyltransferase is implicated in the regulation of cellular lifespan and DNA damage response (DDR). In the pre...

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Detalles Bibliográficos
Autores principales: Bloniarz, Dominika, Adamczyk-Grochala, Jagoda, Lewinska, Anna, Wnuk, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266355/
https://www.ncbi.nlm.nih.gov/pubmed/34139673
http://dx.doi.org/10.18632/aging.203203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266355/
https://www.ncbi.nlm.nih.gov/pubmed/34139673
http://dx.doi.org/10.18632/aging.203203

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