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The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence
Cellular senescence may be a side effect of chemotherapy and other anti-cancer treatments that may promote inflammation and paracrine secondary senescence in healthy tissues. DNMT2/TRDMT1 methyltransferase is implicated in the regulation of cellular lifespan and DNA damage response (DDR). In the pre...
Autores principales: | Bloniarz, Dominika, Adamczyk-Grochala, Jagoda, Lewinska, Anna, Wnuk, Maciej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266355/ https://www.ncbi.nlm.nih.gov/pubmed/34139673 http://dx.doi.org/10.18632/aging.203203 |
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