A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics

Integrin adhesion complexes regulate cytoskeletal dynamics during cell migration. Adhesion activates phosphorylation of integrin-associated signaling proteins, including Cas (p130Cas, BCAR1), by Src-family kinases. Cas regulates leading-edge protrusion and migration in cooperation with its binding p...

Descripción completa

Detalles Bibliográficos
Autores principales: Steenkiste, Elizabeth M, Berndt, Jason D, Pilling, Carissa, Simpkins, Christopher, Cooper, Jonathan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266394/
https://www.ncbi.nlm.nih.gov/pubmed/34169835
http://dx.doi.org/10.7554/eLife.67078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266394/
https://www.ncbi.nlm.nih.gov/pubmed/34169835
http://dx.doi.org/10.7554/eLife.67078

Ejemplares similares