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A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics

Integrin adhesion complexes regulate cytoskeletal dynamics during cell migration. Adhesion activates phosphorylation of integrin-associated signaling proteins, including Cas (p130Cas, BCAR1), by Src-family kinases. Cas regulates leading-edge protrusion and migration in cooperation with its binding p...

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Detalles Bibliográficos
Autores principales:	Steenkiste, Elizabeth M, Berndt, Jason D, Pilling, Carissa, Simpkins, Christopher, Cooper, Jonathan A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266394/ https://www.ncbi.nlm.nih.gov/pubmed/34169835 http://dx.doi.org/10.7554/eLife.67078

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