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12-Epi-Napelline Inhibits Leukemia Cell Proliferation via the PI3K/AKT Signaling Pathway In Vitro and In Vivo

This study aimed to investigate the inhibitory effect of 12-epi-napelline on leukemia cells and its possible mechanisms. The inhibitory effects of 12-epi-napelline on K-562 and HL-60 cells were evaluated using the CCK-8 assay, cell cycle arrest and apoptosis were detected by flow cytometry, and the...

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Detalles Bibliográficos
Autores principales: Han, Jia, Hou, Wei, Cai, Bi-qing, Zhang, Fan, Tang, Jian-cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266464/
https://www.ncbi.nlm.nih.gov/pubmed/34306152
http://dx.doi.org/10.1155/2021/6687519