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Mechanical diversity and folding intermediates of parallel-stranded G-quadruplexes with a bulge
A significant number of sequences in the human genome form noncanonical G-quadruplexes (G4s) with bulges or a guanine vacancy. Here, we systematically characterized the mechanical stability of parallel-stranded G4s with a one to seven nucleotides bulge at various positions. Our results show that G4-...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266575/ https://www.ncbi.nlm.nih.gov/pubmed/34139007 http://dx.doi.org/10.1093/nar/gkab531 |