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Mechanical diversity and folding intermediates of parallel-stranded G-quadruplexes with a bulge

A significant number of sequences in the human genome form noncanonical G-quadruplexes (G4s) with bulges or a guanine vacancy. Here, we systematically characterized the mechanical stability of parallel-stranded G4s with a one to seven nucleotides bulge at various positions. Our results show that G4-...

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Detalles Bibliográficos
Autores principales:	Zhang, Yashuo, Cheng, Yuanlei, Chen, Juannan, Zheng, Kewei, You, Huijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266575/ https://www.ncbi.nlm.nih.gov/pubmed/34139007 http://dx.doi.org/10.1093/nar/gkab531

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