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Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication

Mosquito-borne flaviviruses (MBFVs) including dengue, West Nile, yellow fever, and Zika viruses have an RNA genome encoding one open reading frame flanked by 5′ and 3′ untranslated regions (UTRs). The 3′ UTRs of MBFVs contain regions of high sequence conservation in structured RNA elements known as...

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Detalles Bibliográficos
Autores principales: Akiyama, Benjamin M, Graham, Monica E, O′Donoghue, Zoe, Beckham, J David, Kieft, Jeffrey S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266583/
https://www.ncbi.nlm.nih.gov/pubmed/34133732
http://dx.doi.org/10.1093/nar/gkab462