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Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code

The specific recognition of splice signals at or near exon-intron junctions is not explained by their weak conservation and instead is postulated to require a multitude of features embedded in the pre-mRNA strand. We explored the possibility of 3D structural scaffold of AdML—a model pre-mRNA substra...

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Detalles Bibliográficos
Autores principales: Saha, Kaushik, Fernandez, Mike Minh, Biswas, Tapan, Joseph, Simpson, Ghosh, Gourisankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266590/
https://www.ncbi.nlm.nih.gov/pubmed/34161584
http://dx.doi.org/10.1093/nar/gkab533