MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution

Technical challenges remain in the sequencing of RNA viruses due to their high intra-host diversity. This bottleneck is particularly pronounced when interrogating long-range co-evolved genetic interactions given the read-length limitations of next-generation sequencing platforms. This has hampered t...

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Detalles Bibliográficos
Autores principales: Gallardo, Christian M, Wang, Shiyi, Montiel-Garcia, Daniel J, Little, Susan J, Smith, Davey M, Routh, Andrew L, Torbett, Bruce E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266615/
https://www.ncbi.nlm.nih.gov/pubmed/33849057
http://dx.doi.org/10.1093/nar/gkab231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266615/
https://www.ncbi.nlm.nih.gov/pubmed/33849057
http://dx.doi.org/10.1093/nar/gkab231

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