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MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution
Technical challenges remain in the sequencing of RNA viruses due to their high intra-host diversity. This bottleneck is particularly pronounced when interrogating long-range co-evolved genetic interactions given the read-length limitations of next-generation sequencing platforms. This has hampered t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266615/ https://www.ncbi.nlm.nih.gov/pubmed/33849057 http://dx.doi.org/10.1093/nar/gkab231 |