Chemical and photochemical error rates in light-directed synthesis of complex DNA libraries

Nucleic acid microarrays are the only tools that can supply very large oligonucleotide libraries, cornerstones of the nascent fields of de novo gene assembly and DNA data storage. Although the chemical synthesis of oligonucleotides is highly developed and robust, it is not error free, requiring the...

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Detalles Bibliográficos
Autores principales: Lietard, Jory, Leger, Adrien, Erlich, Yaniv, Sadowski, Norah, Timp, Winston, Somoza, Mark M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266620/
https://www.ncbi.nlm.nih.gov/pubmed/34157124
http://dx.doi.org/10.1093/nar/gkab505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266620/
https://www.ncbi.nlm.nih.gov/pubmed/34157124
http://dx.doi.org/10.1093/nar/gkab505

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