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Insights into xanthine riboswitch structure and metal ion-mediated ligand recognition

Riboswitches are conserved functional domains in mRNA that mostly exist in bacteria. They regulate gene expression in response to varying concentrations of metabolites or metal ions. Recently, the NMT1 RNA motif has been identified to selectively bind xanthine and uric acid, respectively, both are i...

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Detalles Bibliográficos
Autores principales: Xu, Xiaochen, Egger, Michaela, Chen, Hao, Bartosik, Karolina, Micura, Ronald, Ren, Aiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266621/
https://www.ncbi.nlm.nih.gov/pubmed/34125892
http://dx.doi.org/10.1093/nar/gkab486