Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin

How aminoglycoside antibiotics limit bacterial growth and viability is not clearly understood. Here we employ fast kinetics to reveal the molecular mechanism of action of a clinically used, new-generation, semisynthetic aminoglycoside Arbekacin (ABK), which is designed to avoid enzyme-mediated deact...

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Detalles Bibliográficos
Autores principales: Parajuli, Narayan Prasad, Mandava, Chandra Sekhar, Pavlov, Michael Y, Sanyal, Suparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266624/
https://www.ncbi.nlm.nih.gov/pubmed/34125898
http://dx.doi.org/10.1093/nar/gkab495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266624/
https://www.ncbi.nlm.nih.gov/pubmed/34125898
http://dx.doi.org/10.1093/nar/gkab495

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