Beyond small molecules: targeting G-quadruplex structures with oligonucleotides and their analogues

G-Quadruplexes (G4s) are widely studied secondary DNA/RNA structures, naturally occurring when G-rich sequences are present. The strategic localization of G4s in genome areas of crucial importance, such as proto-oncogenes and telomeres, entails fundamental implications in terms of gene expression re...

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Detalles Bibliográficos
Autores principales: Cadoni, Enrico, De Paepe, Lessandro, Manicardi, Alex, Madder, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266634/
https://www.ncbi.nlm.nih.gov/pubmed/33978760
http://dx.doi.org/10.1093/nar/gkab334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266634/
https://www.ncbi.nlm.nih.gov/pubmed/33978760
http://dx.doi.org/10.1093/nar/gkab334

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