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DNA molecular combing-based replication fork directionality profiling

The replication strategy of metazoan genomes is still unclear, mainly because definitive maps of replication origins are missing. High-throughput methods are based on population average and thus may exclusively identify efficient initiation sites, whereas inefficient origins go undetected. Single-mo...

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Detalles Bibliográficos
Autores principales: Blin, Marion, Lacroix, Laurent, Petryk, Nataliya, Jaszczyszyn, Yan, Chen, Chun-Long, Hyrien, Olivier, Le Tallec, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266662/
https://www.ncbi.nlm.nih.gov/pubmed/33836085
http://dx.doi.org/10.1093/nar/gkab219