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Radiation-induced YAP activation confers glioma radioresistance via promoting FGF2 transcription and DNA damage repair

Although radiotherapy is a well-known effective non-surgical treatment for malignant gliomas, the therapeutic efficacy is severely limited due to the radioresistance of tumor cells. Previously, we demonstrated that Yes-associated protein (YAP) promotes glioma malignant progression. However, whether...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Wang, Yan, Zhou, Ding, Wang, Kai, Wang, Xu, Wang, Xiang, Jiang, Yang, Zhao, Min, Yu, Rutong, Zhou, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266683/
https://www.ncbi.nlm.nih.gov/pubmed/34127812
http://dx.doi.org/10.1038/s41388-021-01878-3