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Overexpression of a single ORF can extend chronological lifespan in yeast if retrograde signaling and stress response are stimulated

Systematic collections of single-gene deletions have been invaluable in uncovering determinants of lifespan in yeast. Overexpression of a single gene does not have such a clear outcome as cancellation of its function but it can lead to a variety of imbalances, deregulations and compensations, and so...

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Detalles Bibliográficos
Autores principales: Pogoda, Elzbieta, Tutaj, Hanna, Pirog, Adrian, Tomala, Katarzyna, Korona, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266792/
https://www.ncbi.nlm.nih.gov/pubmed/34052951
http://dx.doi.org/10.1007/s10522-021-09924-z