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Overexpression of a single ORF can extend chronological lifespan in yeast if retrograde signaling and stress response are stimulated
Systematic collections of single-gene deletions have been invaluable in uncovering determinants of lifespan in yeast. Overexpression of a single gene does not have such a clear outcome as cancellation of its function but it can lead to a variety of imbalances, deregulations and compensations, and so...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266792/ https://www.ncbi.nlm.nih.gov/pubmed/34052951 http://dx.doi.org/10.1007/s10522-021-09924-z |