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Toward Better Reproducibility in Experimental Research on New Agents for Pulmonary Hypertension. An Analysis of Data from Four Hundred Animal Studies
PURPOSE: Pre-clinical data can provide a rationale for subsequent clinical trials and they are the first step in drug development; however, the therapeutic effect observed during animal studies does not necessarily translate to similar results in humans. METHODS: Taking the example of pulmonary hype...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266793/ https://www.ncbi.nlm.nih.gov/pubmed/33294946 http://dx.doi.org/10.1007/s10557-020-07109-3 |