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Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer

Exosomes are carriers of intercellular information that regulate the tumor microenvironment, and they have an essential role in drug resistance through various mechanisms such as transporting RNA molecules and proteins. Nevertheless, their effects on gemcitabine resistance in triple-negative breast...

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Detalles Bibliográficos
Autores principales: Li, Ting, Tao, Zhonghua, Zhu, Yihui, Liu, Xiaojia, Wang, Leiping, Du, Yiqun, Cao, Jun, Wang, Biyun, Zhang, Jian, Hu, Xichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266800/
https://www.ncbi.nlm.nih.gov/pubmed/34238922
http://dx.doi.org/10.1038/s41419-021-03963-7