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DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy
Genomic instability is the hallmark of various cancers with the increasing accumulation of DNA damage. The application of radiotherapy and chemotherapy in cancer treatment is typically based on this property of cancers. However, the adverse effects including normal tissues injury are also accompanie...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266832/ https://www.ncbi.nlm.nih.gov/pubmed/34238917 http://dx.doi.org/10.1038/s41392-021-00648-7 |