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EGR1 and RXRA transcription factors link TGF-β pathway and CCL2 expression in triple negative breast cancer cells

Transforming growth factor beta (TGF-β) is the main cytokine responsible for the induction of the epithelial-mesenchymal transition of breast cancer cells, which is a hallmark of tumor transformation to the metastatic phenotype. Recently, research demonstrated that the chemokine CCL2 gene expression...

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Detalles Bibliográficos
Autores principales: Gorbacheva, Alisa M., Uvarova, Aksinya N., Ustiugova, Alina S., Bhattacharyya, Arindam, Korneev, Kirill V., Kuprash, Dmitry V., Mitkin, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266896/
https://www.ncbi.nlm.nih.gov/pubmed/34239022
http://dx.doi.org/10.1038/s41598-021-93561-6