IIIM-941, a Stilbene Derivative Inhibits NLRP3 Inflammasome Activation by Inducing Autophagy

Aberrant activation of NLRP3 inflammasome has been implicated in several inflammatory diseases. Autophagy is one of the primary mechanisms that regulate NLRP3 inflammasome activity. In this study, we attempted to target NLRP3 inflammasome activity by a synthetic compound IIIM-941. We found that IIIM...

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Detalles Bibliográficos
Autores principales: Ali, Mehboob, Gupta, Mehak, Wani, Abubakar, Sharma, Ankita, Abdullaha, Mohd, Kour, Dilpreet, Choudhary, Sushil, Bharate, Sandip B., Singh, Gurdarshan, Kumar, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267097/
https://www.ncbi.nlm.nih.gov/pubmed/34248643
http://dx.doi.org/10.3389/fphar.2021.695712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267097/
https://www.ncbi.nlm.nih.gov/pubmed/34248643
http://dx.doi.org/10.3389/fphar.2021.695712

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