Apatinib enhances the anti-tumor effect of paclitaxel via the PI3K/p65/Bcl-xl pathway in triple-negative breast cancer

BACKGROUND: Apatinib is a new generation of small molecule tyrosine kinase inhibitor, which can highly selectively inhibit phosphorylation of vascular endothelial growth factor receptor 2 (VEGFR-2). This study aimed to investigate the synergistic effects of apatinib and paclitaxel (PTX) on triple-ne...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Deng, Shuzhen, Zhang, Yifan, Wang, Chaokun, Hu, Xiaochen, Kong, Dejiu, Liang, Gaofeng, Yuan, Xiang, Li, Yuanpei, Wang, Xinshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267319/
https://www.ncbi.nlm.nih.gov/pubmed/34277801
http://dx.doi.org/10.21037/atm-21-805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267319/
https://www.ncbi.nlm.nih.gov/pubmed/34277801
http://dx.doi.org/10.21037/atm-21-805

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