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Selective activation of cannabinoid receptor 2 regulates Treg/Th17 balance to ameliorate neutrophilic asthma in mice

BACKGROUND: The cannabinoid receptor 2 (CNR2) plays a critical role in relieving asthma, with the mechanism still unclear. We aimed to investigate the mechanism of the CNR2 agonist (β-caryophyllene, β-Car) in regulating the balance of regulatory T cells (Treg) and T helper cell 17 (Th17) and thus it...

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Detalles Bibliográficos
Autores principales: Wei, Chaochao, Huang, Linhui, Zheng, Yamei, Cai, Xingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267324/
https://www.ncbi.nlm.nih.gov/pubmed/34277815
http://dx.doi.org/10.21037/atm-21-2778