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Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma

Osteosarcoma remains one of the deadliest cancers in pediatrics and young adults. We administered two types of immunotherapies, oncolytic virotherapy and immune checkpoint inhibition, to two murine osteosarcoma models and observed divergent results. Mice bearing F420 showed no response, whereas thos...

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Detalles Bibliográficos
Autores principales: Wedekind, Mary Frances, Miller, Katherine E., Chen, Chun-Yu, Wang, Pin-Yi, Hutzen, Brian J., Currier, Mark A., Nartker, Brooke, Roberts, Ryan D., Boon, Louis, Conner, Joe, LaHaye, Stephanie, Kelly, Benjamin J., Gordon, David, White, Peter, Mardis, Elaine R., Cripe, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267546/
https://www.ncbi.nlm.nih.gov/pubmed/34278266
http://dx.doi.org/10.1016/j.isci.2021.102759