Cargando…

Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis

Liver fibrosis is a common characteristic of chronic liver diseases. The activation of hepatic stellate cells (HSCs) plays a key role in fibrogenesis in response to liver injury, yet the mechanism by which damaged hepatocytes modulate the activation of HSCs is poorly understood. Our previous studies...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Bichen, Lapenta, Kalina, Wang, Qi, Nam, Jin Hyun, Chung, Dongjun, Robert, Marie E., Nathanson, Michael H., Yang, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267550/
https://www.ncbi.nlm.nih.gov/pubmed/34146542
http://dx.doi.org/10.1016/j.jbc.2021.100887