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Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis
Liver fibrosis is a common characteristic of chronic liver diseases. The activation of hepatic stellate cells (HSCs) plays a key role in fibrogenesis in response to liver injury, yet the mechanism by which damaged hepatocytes modulate the activation of HSCs is poorly understood. Our previous studies...
Autores principales: | Zhang, Bichen, Lapenta, Kalina, Wang, Qi, Nam, Jin Hyun, Chung, Dongjun, Robert, Marie E., Nathanson, Michael H., Yang, Xiaoyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267550/ https://www.ncbi.nlm.nih.gov/pubmed/34146542 http://dx.doi.org/10.1016/j.jbc.2021.100887 |
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