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The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds

Mucus forms an important protective barrier that minimizes bacterial contact with the colonic epithelium. Intestinal mucus is organized in a complex network with several specific proteins, including the mucin-2 (MUC2) and the abundant IgGFc-binding protein, FCGBP. FCGBP is expressed in all intestina...

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Detalles Bibliográficos
Autores principales: Ehrencrona, Erik, van der Post, Sjoerd, Gallego, Pablo, Recktenwald, Christian V., Rodriguez-Pineiro, Ana M., Garcia-Bonete, Maria-Jose, Trillo-Muyo, Sergio, Bäckström, Malin, Hansson, Gunnar C., Johansson, Malin E.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267560/
https://www.ncbi.nlm.nih.gov/pubmed/34126068
http://dx.doi.org/10.1016/j.jbc.2021.100871