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The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds
Mucus forms an important protective barrier that minimizes bacterial contact with the colonic epithelium. Intestinal mucus is organized in a complex network with several specific proteins, including the mucin-2 (MUC2) and the abundant IgGFc-binding protein, FCGBP. FCGBP is expressed in all intestina...
Autores principales: | Ehrencrona, Erik, van der Post, Sjoerd, Gallego, Pablo, Recktenwald, Christian V., Rodriguez-Pineiro, Ana M., Garcia-Bonete, Maria-Jose, Trillo-Muyo, Sergio, Bäckström, Malin, Hansson, Gunnar C., Johansson, Malin E.V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267560/ https://www.ncbi.nlm.nih.gov/pubmed/34126068 http://dx.doi.org/10.1016/j.jbc.2021.100871 |
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