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Modulation of Tumor Microenvironment to Enhance Radiotherapy Efficacy in Esophageal Squamous Cell Carcinoma by Inhibiting Carbonic Anhydrase IX

The radiotherapy outcomes of patients with advanced esophageal squamous cell carcinoma (ESCC) remain poor due to hypoxia. Carbonic anhydrase IX (CAIX) is a membrane-associated enzyme that induces hypoxia, extracellular acidity, and upregulation of hypoxia-related factors in tumor microenvironment, t...

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Detalles Bibliográficos
Autores principales: Xu, Pengqin, Zhang, Yu, Ge, Fanghong, Zhang, Fuming, He, Xia, Gao, Xingya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267588/
https://www.ncbi.nlm.nih.gov/pubmed/34249682
http://dx.doi.org/10.3389/fonc.2021.637252