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Ovarian cancer modulates the immunosuppressive function of CD11b(+)Gr1(+) myeloid cells via glutamine metabolism

OBJECTIVE: Immature CD11b (+) Gr1(+) myeloid cells that acquire immunosuppressive capability, also known as myeloid-derived suppressor cells (MDSCs), are a heterogeneous population of cells that regulate immune responses. Our study's objective was to elucidate the role of ovarian cancer microen...

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Detalles Bibliográficos
Autores principales: Udumula, Mary P., Sakr, Sharif, Dar, Sajad, Alvero, Ayesha B., Ali-Fehmi, Rouba, Abdulfatah, Eman, Li, Jing, Jiang, Jun, Tang, Amy, Buekers, Thomas, Morris, Robert, Munkarah, Adnan, Giri, Shailendra, Rattan, Ramandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267600/
https://www.ncbi.nlm.nih.gov/pubmed/34144215
http://dx.doi.org/10.1016/j.molmet.2021.101272