Hsp70 Interacts with the TREM-1 Receptor Expressed on Monocytes and Thereby Stimulates Generation of Cytotoxic Lymphocytes Active against MHC-Negative Tumor Cells

The search for and analysis of new ligands for innate immunity receptors are of special significance for understanding the regulatory mechanisms of immune response. Here we show that the major heat shock protein 70 (Hsp70) can bind to and activate TREM-1, the innate immunity receptor expressed on mo...

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Detalles Bibliográficos
Autores principales: Sharapova, Tatiana N., Romanova, Elena A., Ivanova, Olga K., Yashin, Denis V., Sashchenko, Lidia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267615/
https://www.ncbi.nlm.nih.gov/pubmed/34206968
http://dx.doi.org/10.3390/ijms22136889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267615/
https://www.ncbi.nlm.nih.gov/pubmed/34206968
http://dx.doi.org/10.3390/ijms22136889

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